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Although three-generation IVF will screen the embryo chromosome genes, but at present, three-generation IVF can screen only 274 kinds of diseases, and the world is known to be more than 3,000 kinds of genetic diseases, so not all the diseases three-generation IVF are screened to exclude. In order to ensure the success rate of three-generation IVF as well as the birth of a healthy fetus, hospitals are required to check the chromosomes of both husband and wife before three-generation IVF to determine whether the disease can be ruled out through three-generation IVF technology.

Among the main causes of female infertility, chromosomal abnormalities almost dominate except for uterine diseases and endometrial causes. In particular, the probability of embryos having chromosomal aneuploidy problems is close to 80% in women over 37 years of age and higher than 90% in women over 42 years of age.

Chromosomal abnormalities in embryos will not only lead to embryos not being able to land, wasting the activation of the transfer, but even if they do, the likelihood of the fetus being sick is also very high; according to big data, the older the couple is, the higher the probability of chromosomal abnormalities occurring, and through the three-generation IVF embryo screening technology, chromosomal abnormalities of embryos can be screened out to improve the rate of embryo landings, thus improving the chances of pregnancy.

To do three-generation IVF requires indications, only chromosomal abnormalities, the existence of genetic history, multiple implantation failure can be carried out three-generation IVF to help pregnancy, and before helping pregnancy need to men and women to provide relevant examination reports surface existence of indications, otherwise only one generation, two generations of IVF. At present, the three generations of IVF technology can screen the disease is limited, the vast majority of genetic diseases through three generations of IVF can not be excluded, so you need to couples first chromosome examination, clear whether the three generations of IVF treatment.

Although it is said that three-generation IVF will carry out genetic screening of embryos, due to national policies, limitations of three-generation IVF technology and eugenic purposes, it is necessary for both spouses to carry out chromosome tests before three-generation IVF can be carried out to help pregnancy.