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Blastocyst PGS screening is an important technique in the assisted reproduction process to screen for healthy potential embryos through genetic testing of blastocysts to improve IVF success rates. However, a number of factors can lead to an increased elimination rate of blastocyst PGS screening, affecting the final pregnancy outcome. At the same time, the pass rate of genetic screening of blastocysts in three generations of IVF is a matter of great concern.

What are the factors that can lead to a higher elimination rate of blastocyst PGS screening?

First of all, egg quality is one of the main reasons for the increase of blastocyst PGS screening elimination rate. Both the number and quality of mature eggs have a direct impact on the health of blastocysts. If the eggs themselves have chromosomal abnormalities or genetic disorders, the number of healthy embryos screened will be reduced, even if genetic testing is performed during blastocyst formation.

Impact of the Fertilization Process

Second, problems during fertilization may also lead to higher blastocyst PGS screening elimination rates. If the combination of sperm and egg results in conditions such as abnormal chromosome splitting or fusion of multiple chromosomes, this can result in genetic abnormalities in blastocysts, which are ultimately eliminated.

Impact of Blastocyst Culture Conditions

In addition, blastocyst culture conditions are critical to their development. If the culture environment is poor, the supply of nutrients is insufficient or the temperature and humidity are not suitable, it will affect the healthy development of blastocysts and increase the possibility of genetic abnormalities.

Pass rate of three-generation IVF blastocyst genetic screening

Three-generation IVF blastocyst genetic screening refers to the whole genome sequencing of blastocysts using more advanced technology on the basis of PGS screening. This technology is able to detect more risks of genetic diseases, improving the accuracy and safety of embryo screening. The pass rate of three-generation IVF blastocyst genetic screening is generally around 70%, and the specific situation needs to be considered according to individual differences, genetic factors and other comprehensive considerations.

All in all, the reasons for the increase in the elimination rate of blastocyst PGS screening are multi-faceted, and need to be comprehensively assessed from the aspects of egg quality, fertilization process, and blastocyst culture conditions. The pass rate of three-generation IVF blastocyst genetic screening is higher, but it still needs to be selected and operated according to individual conditions. We hope this information can help you better understand the knowledge about Blastocyst PGS screening.