添伢网

With the opening of the two-child policy, IVF has become a way for older people to achieve fertility. Before undergoing assisted reproductive technology treatment, then, how to cooperate with doctors for IVF technology treatment?

1 What is the general treatment process of IVF?

Step 1 Make an appointment for consultation

You need to consult the fertility consultant at your domestic service provider or pay attention to our official WeChat of Fertility Medicine in advance to know the schedule of IVF doctors and make an appointment for the consultation.

Step 2 Waiting for the consultation

Bring all your recent labs or checkups with you and wait for the information to indicate your appointment time.

Step 3 Consultation

During the consultation, both husband and wife patiently cooperate with the doctor to ask about your medical history, so that the doctor can better understand your physical condition and choose a suitable treatment plan.

Step 4 Pre-operative preparation

Prepare all kinds of documents, such as ID card, marriage certificate, birth certificate, etc., carry out the routine pre-operative examination to confirm that the patient has the basic conditions and indications for receiving assisted reproduction technology treatment, and sign the informed consent form. Routine pre-operative laboratory tests include blood routine and blood type, hepatitis series, chlamydia, anti-sperm antibodies, HIV and syphilis serum screening test for both couples; basic female examination includes hormone six, ultrasound, and tubal imaging; men are required to retain semen for routine semen analysis before the procedure, including semen volume, semen PH, semen liquefaction time, sperm morphology, density, and viability, and so on.

If you meet the indications for IVF treatment and have made the above pre-procedure preparations you are ready to enter the treatment cycle.

Step 5 Conduct the IVF cycle

2 Specific treatment steps of IVF

1. Induction and monitoring of ovulation

Under the natural state, a woman only releases one mature egg per menstrual cycle. In order to increase the success rate of IVF pregnancy, drugs are needed to induce the development of a sufficient number of mature eggs to combine with sperms.

Currently, the drugs we commonly use to induce ovulation include gonadotropins, gonadotropin-releasing hormone analogs, etc. Gonadotropins are categorized into natural and recombinant depending on their source, and the natural source is the most important drug for egg growth and development, with a complete enzyme system in the human body. Recombinant gonadotropin preparations are produced by genetic engineering techniques, in addition, gonadotropin-releasing hormone analogs play a key role in the regulation of the reproductive system.

These drugs serve to allow better control of ovarian stimulation in order to select the optimal time to induce ovulation. Once the egg has grown and developed to the right size, we inject chorionic gonadotropin to allow the egg to finally mature.

During ovulation induction, your doctor will implement a treatment plan that takes into account the cause of your infertility and the sensitivity of your hormone levels to medications.

During ovulation induction, the medical staff utilizes vaginal ultrasound, estradiol preparation and urine LH measurements to observe the number and size of the follicles and their growth rate, so that the number of follicles can be controlled by increasing or decreasing the dose of the medication or by adjusting the time of administration to achieve optimal stimulation. When the follicle develops to about 18MM, intramuscular injection of chorionic gonadotropin (HCG) induces ovulation 34~36 hours later for egg retrieval.

2. Egg retrieval and sperm retrieval

Through a set of puncture negative pressure suction system, the doctor will puncture and suction the mature follicles and collect the follicular fluid containing oocytes. At the same time, the man's semen is drained into a clean, non-toxic container and placed at room temperature to liquefy naturally, and then placed in an incubator through optimized processing.

3、In vitro fertilization and embryo culture

The first generation of IVF technology involves removing eggs for evaluation and washing and evaluating sperm, then placing qualified eggs and sperm in a culture medium to fertilize them naturally.

The second generation IVF technique involves removing the granulosa cells around the egg line cells, washing and evaluating the sperm and then aspirating a single sperm to inject into the egg and continue the fertilization culture, where a physician in the laboratory determines if fertilization is successful and if so evaluates the quality of the embryo on day 2.3.4.5, respectively.

The third generation IVF technique is to culture the sperm and eggs first and then conduct PGD and PGS tests to rule out genetic diseases before implantation of the embryos to make their embryos healthier.

4. Embryo Transfer and Luteal Support

The well-developed embryos are placed back into the uterine cavity through a special transfer catheter to continue their growth and development. The number of embryos implanted into the uterus depends on the woman's age, the cause of infertility, etc. The maximum number of embryos should not be more than 3. Extra embryos of satisfactory quality can be frozen and preserved for next time upon request. After embryo implantation, the patient may face luteal insufficiency should be luteal support.

5、Precautions after embryo transfer

After embryo transfer, women should rest in bed for 15-30 minutes, and during this period they should pay attention to avoiding heavy physical labor, strenuous exercise, and forbidding sexual intercourse, but it is not necessary to stay in bed absolutely.

Diet should be light and easily digestible food to avoid diarrhea. Keep in a good mood, good mood can improve and coordinate the excitement of the cerebral cortex and nervous system. Promote embryo implantation individually with the occurrence of gastrointestinal discomfort, urinary and respiratory difficulties, vaginal bleeding, lower abdominal pain and other symptoms should be promptly come to the hospital for review, so as not to delay treatment.

14 days after the transplantation of blood or urine check HCG, the test results are negative then stop the drug, positive then continue to use the drug. And four weeks after the transplantation of vaginal ultrasound, if the uterine cavity to see the gestational sac or embryonic buds, fetal heartbeat, it is a sign of successful clinical pregnancy.

Finally, there are some abnormalities occurring in the treatment process of IVF, so how can we prevent and control them?

3 How to prevent abnormalities in IVF?

Ovarian hyperstimulation syndrome is a common complication in the treatment process, which usually does not require treatment, but must be closely followed up, and if there is a tendency to aggravate, it should be actively treated.

Some women may experience poor ovarian response during ovulation induction, and your healthcare provider will check your hormone levels to adjust the dosage of medication or readjust the regimen for the next cycle.

You may not have thought that multiple pregnancies are also a common complication of IVF. Multiple pregnancies are prone to pregnancy complications such as gestational hypertension, excessive amniotic fluid, severe anemia, miscarriage, and preterm delivery, which can be very harmful to both the newborn and the mother. If more than 3 pregnancies occur, selective embryo reduction must be performed.

Tips.

In conclusion, a woman's age, ovarian function, tubal fluid, psychological factors, social environment, etc. can affect the outcome of IVF treatment to varying degrees, so please trust your doctor and choose a treatment plan that is right for you, which is very important to improve your chances of getting pregnant. During the course of treatment, mutual care, mutual support, meticulous communication and the courage to face problems together between you and your partner will make your relationship deeper. Maintaining a relaxed and optimistic attitude can improve a woman's chances of conceiving. Your good attitude, together with your positive attitude towards the treatment, will mean the beginning of success.