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Patients undergoing third generation IVF need to have their embryos cultured to the blastocyst stage and then screened based on the embryonic cells. It is understood that there are three types of third-generation IVF blastocyst screening programs, in addition to the screening of monogenic genetic diseases such as hemophilia, fragile X syndrome, polycystic kidney disease and other conditions, but also can screen whether the number of chromosomes is abnormal, chromosomal structural variations, etc. Specific screening programs and diseases, you can go to the hospital to consult with the relevant doctors to understand.

The third generation IVF PGT screening is mainly divided into three types, namely, chromosome aneuploidy genetic screening, chromosome structural variant genetic testing and single gene genetic testing, which can help patients suffering from genetic diseases screen whether the blastocysts are normal or not, so as to reduce the chances of conceiving a problematic fetus. If you do not know the items that need to be screened for third generation IVF, then you can refer to the following content.

1、Single gene genetic disease

Third-generation IVF technology usually screens for single-gene genetic disease, which is a disease that occurs under the control of a pair of alleles, and there are many kinds of diseases, but the third-generation IVF is only able to screen for some common diseases, such as thalassemia, hemophilia, Fragile X Syndrome, Polycystic Kidney Disease, Rett's Syndrome and so on.

2. Chromosome number

Abnormal chromosome number is caused by abnormal cell division, which will lead to a variety of poor development of the fetus, and the third generation IVF can mainly screen the blastocysts for the presence of 21-trisomy, Klinefelter syndrome, 18-trisomy, 13-trisomy and other diseases.

3、Chromosome structure

The third generation IVF blastocyst screening program includes chromosome structure variation, which is a type of chromosome variation, the specific types are very diverse, such as balanced translocation, Robertson's translocation, inversion, etc., which can lead to a variety of genetic diseases in patients.

The technical testing of third-generation IVF can help screen out chromosomal abnormalities or risks of genetic diseases in the embryos and select healthy blastocysts for transplantation, improving the success rate and health of IVF. This facilitates eugenics and improves the pregnancy rate of healthy fetuses.